Eventually, one company ProStraken acquired the full rights to RU58841 and changed its name to PSK3841. Written by Kartik Kumar Rathi Updated On February 1, 2023 Compound Summary Class of Compound Peptide (NSAA)/SARMs Mechanism of Action RU58841 8% Powerful Topical DHT Inhibitor RU58841: is an androgen receptor antagonist. Please Log in or Create an account to join the conversation. If you buy something through a link on this page, we may earn a small commission. Audio mixing is the process of taking recorded tracks and blending them together. I use a boar brush to exfoliate. This article is intended for educational / informational purposes only. Truth or Myth?Continue. After dedicating over 8 years to extreme self-improvement, I have created "More Plates More Dates" as a one stop shop for helping you to get yourself on the right path to the "best you" possible too. Read More Creatine Causes Hair Loss. Add to Favorites . However, there is a lot of misinformation floating around on the internet about the use and side effects of DHT blockers and many unsubstantiated claims about its alternatives. So definitely anti androgen activity there. Very fast shipping and excellent product from anageninc. Shedding stopped almost immediately after starting treatment. Apply RU-58841 liquid once daily, recommended time is in the evening. If you want to mix the standard concentration, use 2.5 grams of raw RU58841 powder in a 50ml K&B solution to achieve a 5% RU58841 solution of 50mg/ml. Perhaps exhibits less efficacy/ability to deliver RU58841 to the hair follicles than a 70%/30% Ethanol/Propylene Glycol solution can. I will be using RU for the rest of my life unless something better gets invented. CAS No. It does if you use enough solution for the amount of RU powder you're reconstituting, as well as shake/stir it good enough. Since then, similar studies on humans have not been conducted or published in peer-reviewed medical journals. For instance, you should be aware that RU58841 not only blocks DHT but all other androgens including testosterone. I keep those sealed in several ziplock bags, in another closed container to ensure no water somehow seeps in and hits the powder. The main aim of these scientists was to develop a potent medication that would effectively manage acne and androgenic alopecia when applied topically while avoiding/limiting systemic side effects that are commonly observed with other anti-androgens. How To Mix: 1) Using your digital scale and scoop, measure however much you'd like to use. RU58841 is a non-steroidal anti-androgenic medication that was initially developed in the 1980s as a topical treatment remedy for acne and male pattern baldness androgenetic alopecia. This field is for validation purposes and should be left unchanged. It's also still cold enough to offset degradation to a large degree, but not cold enough to cause crystallization of the powder in the solution basically. Add 2.5 grams of powder to the empty beaker on the scale until you see the scale reading 2.5 grams. It was renamed after newer companies bought the rights to the original product, RU58841. Unfortunately, I doubt we will ever know it, Blocking 5a-reductase to tackle hair loss is like killing a fly with a bazooka. All the benefits of DHT are left intact when you use RU58841. My raw RU powder is always sealed in zip-locks though in the freezer. The Bitcoin savings is appreciated, and makes this affordable where as previously I could not afford this. It seems that the combo hits things from different angles to . This is known as a vehicle. As opposed to pre-mixed RU58841 solutions, all RU58841 raw powder (unmixed) should always be kept in the freezer. 2) At the same time order off of eBay or Amazon a 0.001 gram digital scale. Next, pour the 50ml of K&B solution into the beaker with the 2.5 grams of RU58841 raw powder. The raw powder form is a little cheaper and gives a bit more of flexibility. Hold the can upside down and press the nozzle to put foam on your fingers. Copyright 2022 More Plates More Dates All Rights Reserved. Take, for instance, a little drug called RU58841. Read More 6 Best Hair Fibers to Effortlessly Conceal Your Hair LossContinue, The Food and Drug Administration approved the use of finasteride in 1997 for, Read More Topical Finasteride for Hair Loss: Better than Oral?Continue, In August 2011, a cosmeceutical company Divine Skin Inc., released a new molecule to, Read More Nanoxidil for Hair Loss: Efficacy, Side-Effects, vs. MinoxidilContinue. Hypothetically, lets say you want to make a 5% strength 50mg/ml RU58841 solution (the most popular dosage/strength). Place your beaker/cup bottle on top of the scale, measure out your 3 grams of RU58841 and place it inside. This means that if there are any side effects, then they are actually unknown. 0.001g Scale (roughly $30.00) 8. There is also another popular one (as mentioned previously) called KB. This sebum reduces the penetrative value of RU58841. Don't use more than 100mg *ever* although its good to start off for the first month or so at a higher dosage like 100mg only to kickstart the whole process and any potential regrowth. I was nearly at 30y. Its a big myth that RU58841 is unstable at room temperature. Anageninc is top notch on quality and service. I find it rare for someones scalp to be irritated by the PG/Ethanol to the point of needing K&B instead as the carrier. We won't share your information with anyone. This non steroidal topical androgen antagonist was investigated for therapeutic value in androgenetic alopecia and acne. If you follow the storage recommendation outlined above in your research, you will maximize the potency and longevity of your RU58841. A daily dose of 50 mg applied in areas that are affected by alopecia will usually suffice. ''I have hope for life man'' - buckthorn, 2018. The Ru58841 does what its supposed to do, way less oily surface on the research subject. The material published on hairverse.com is not intended as medical advice, diagnosis, or recommended treatment. No portion of this page may be duplicated without consent. If you need to make 8% RU, you need to add 4.8 grams of RU. RU58841 Batch RU1007 RU58841PG8 Concentration Audit, RU58841 Batch RU1008 RU58841PG5 Concentration Audit, RU58841 Batch RU1009 RU58841KB5 Concentration Audit, RU58841 Batch RU1010 RU58841PG5 Concentration Audit, RU58841 Batch RU1010 RU58841KB5 Concentration Audit, RU58841 Batch RU1011 RU58841PG5 Concentration Audit, RU58841 Batch RU1011 (Retest) RU58841PG5 Concentration Audit, RU58841 Batch RU1011-2 RU58841PG5 Concentration Audit, RU58841 Batch RU1011 RU58841KB5 Concentration Audit, RU58841 Batch RU1014 RU58841PG5 Concentration Audit. Minoxidil is an antihypertensive vasodilator medication. The pre-made solution comes in a concentration of 5% RU58841, at a dose of 50 mg/ml. I am beyond pleased with this product and will recommend to anyone experience hair loss. A few monkey-based studies have been done, which determined the optimal dosing of RU58841 to be 5%, and one study compared it against finasteride. This makes vendors mess around with the concentration and purity of the product. Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques. For more information, please see our Choose products you need for your research. 1 Diffuse thinner here with pretty long hair. Small bottles 6. This makes the fridge ideal for the storage of mixed solutions. Ordered multiple times and only had an issue once with damaged shipment. Great product, it actually works. Very effective product. Topical Finasteride for Hair Loss: Better than Oral? If you already use Minoxidil liquid every day, you want to use RU58841, and your dose has consistently proved to be constant between the two compounds, you may be in the ideal position to use your Minoxidil liquid as your mixing solution for RU58841. E Schimmer, Good product and really quick delivery to uk. Excellent customer service! Using a dropper, apply 1 ml of the 5% solution on the areas that have suffered hair loss. After we receive your order, we will ship your product within 24-48 business hours. First is cheaper, second is more straightforward. It can easily be bought on Amazon, drug store/chemist and even some grocery stores. It is hoped that future studies will document the side effects of using RU58841. IE; RU, SETI, etc. RU 58841, a non-steroidal anti-androgen (NSAA), is a potent compound used to combat Androgenic Alopecia, particularly Male Pattern Baldness (MPB). It prevents miniaturization by blocking DHT, Testosterone, and other androgens from attaching to the hair follicle. The compound works by restricting to the androgen receptors in the scalp and forestalling the transformation of testosterone to dihydrotestosterone (DHT), which is known to add to balding. Submit your order! I know it's the Tretinoin because I've been spot testing. Essentially, to prevent degradation of the compound, you simply must make sure it's stored out of any direct light and it's in a cold enough temperature. Even at high doses of up to 0.01 milligrams, the action was still limited to the site of application a much-desired relief for the researchers. Despite most people giving attention mostly to the topical formulations, studies now show that oral minoxidil could, Read More Oral Minoxidil for Hair Loss: Better than Topical?Continue. Will be ordering again. Too soon to tell really, but Im optimistic. The phase 1 trial involved the application of 5% solution twice daily for 4 weeks, and the phase 2 trial compared the placebo to 2.5% and 5% solutions of RU58841 for 6 months. A controlled study of the effects of RU58841, a nonsteroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosteroneconditioned nude mice. Add 2.5 grams of powder to the empty beaker on the scale until you see the scale reading 2.5 grams. Bonnke holds a Bachelor of Science and currently seeks for Bachelor of Medicine, Bachelor of Surgery (M.B.B.S. Do not apply it on raw skin. Archived post. The method of intake may depend on if you are using RU58841 for hair growth or treating a particular skin disorder. Bonnke Arunga is a senior medical student and an expert health writer. I had two very noticeable bald patches forming after 6 months of TRT and within about 6 weeks of daily application of RU58841 it all re-grew back like nothing happened. They fixed right away without any question. Read our advertising policy. Otherwise, the hairs in that region will also grow thicker over a period of time. RU58841 goes by several names. However, the fact remains that it is not recognized or regulated by the FDA. Any suggestions to help us improve this this sub are always welcome. VitaminP. It is actually quite simple how to mix the two, and it simply involves some basic math. 6 Best Hair Fibers to Effortlessly Conceal Your Hair Loss. The company was acquired by a Japanese company called Kyowa Kurin, after which the project got canceled for monetary reasons. K&B solution is 60% Ethanol, 35% Deionized Water, and 5% K&B Emulsifiers. I have been buying this for a few years and it really does the job of stopping my DHT levels locally instead of systematic. The link is on the bottom right of every page. Here is the reason: RU58841 competitively binds to the receptors of DHT. The overall effect is really noticeable as can be seen in this RU58841 before and after comparison below. RU58841 is an effective enemy of androgen compound that has acquired prominence among people trying to treat balding. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. This category only includes cookies that ensures basic functionalities and security features of the website. Helping one another to deal with hair loss . (1997). Wanna Be Loser. Cookie Notice RU58841 is a bit watery so it is best to apply within and behind the hairline. Been using RU for quite some time now, and I constantly order the premixed for simplicity. The problem is that any treatment which reduces DHT, usually by inhibiting 5-alpha-reductase (drugs like Finasteride), can cause side effects around the body. Posts: 3384. Right now, you are probably aware that hair loss occurs due to the action of DHT on the hair follicles. By Bonnke Arunga, MBBS Updated on March 9, 2023 Reviewed by dermatologistDr. Suneil Gandhi, MD. RU-58841, also known as PSK-3841 or HMR-3841, is a nonsteroidal antiandrogen (NSAA). It is also known as PSK-3841 . Once its crystal clear your solution is ready to go, and you can get your funnel and 50ml+ K&B container and pour the solution through the funnel back into the empty bottle you have to store your solution in. Less than 100mg I'm safe from sides. It is important to store RU58841 in a dry, dark, and cool place as it degrades in heat and sunlight. If you choose instead to add the RU direct into the Minoxidil, do it slowly and carefully (no shit). Could be in my head, but would be nice if the batches were atleast from the past 3-6 months. We strive to achieve absolute first class customer service as well as extremely high quality products! This is the only solution for hair loss period. This product is already mixed and ready to for use. As a result, there are no guarantees that you will get what you see advertised. RU58841 can be either bought in a pre-made solution or as the raw powder form. and our 4) Using your 1ml dropper again, pour 0.3ml of PG into the bottle and mix it again with the RU and everclear. The costumer service was awesome and they are really available for any further questions. The mere fact that the effect of RU58841 does not interfere with the synthesis of DHT and testosterone, makes it a very promising drug. I typically mix the RU and everclear a little more by squeezing in and squeezing out the mixed solution with the dropper. The purpose of this is so we can determine what 3 grams of RU5881 powder is without the beaker screwing up our measurement. Thanks anagen. 3. It needs to penetrate the skin and works it magic where the hair follicle lives. RU-58841 MezogenRX. Get New Research, Treatments, and Discoveries Delivered to your Inbox. Nanoxidil for Hair Loss: Efficacy, Side-Effects, vs. An example is enzulutamide which is structurally similar to RU58841 and is stable for a minimum of 2 years. Very pleased with their customer service! By clicking Accept, you consent to the use of ALL the cookies. However if you wish to make your own solution without the minoxidil, you can use ethanol to do so. RU58841 is stable for at least 2 years at room temperature. It is used as a hair loss treatment, and gives you an aesthetic look! Stainless Steel: Our digital kitchen scale has a stainless-steel surface that's easy to clean. As a result, you should actively think through it and decide if it is indeed the medication you want. Subscribe and get my 20 Underground Bodybuilding Secrets You Wont Find On Google E-Book 100% FREE, There are advantages and disadvantages to mixing your RU58841 with Minoxidil liquid, What You Will Need To Mix Your Own RU58841 And Minoxidil Combination Solutions, Adding The RU58841 Powder To The Minoxidil Liquid Solution, Cheaper if you already use Minoxidil liquid every day, Efficient as Minoxidil already comes in separate 60 ml bottles (very close to the standard 50ml PG + Ethanol solutions we use to measure and mix our RU58841, Requires that you use Minoxidil every single time you apply RU58841 because they are mixed. 5) Buy yourself a small measuring spoon, just get something cheap but SMALLeven from a cheap 'Dollar Store'. Make sure your minoxidil does not have any water in the ingredients. You must log in or register to reply here. Well done guide my man, but do you have any before/after pictures? all in my family,Dad n Mum ,all Males are bald! Thank you received: 1193. Been wondering if there's some composition or form of RU or something to mix it with to make your scalp respond or something. If it does, and you mix it with RU then the RU will not work. More like this: 5 months of hairloss treatment 37 /r/femalehairloss, 2023-04-14, 00:37:58 Has anyone seen better . DHT Blockers for Hair Loss: An In-Depth Overview, 5 Best LLLT Devices: Laser Treatment for Hair Loss, https://doi.org/10.1016/0960-0760(94)90250-X, https://doi.org/10.1046/j.1365-2133.1997.19382053.x, https://international.kyowa-kirin.com/share/pdf/press-release-prostrakan-rebrands-as-kyowa-kirin-18-04-16.pdf, https://www.infona.pl/resource/bwmeta1.element.elsevier-391c502a-853e-3678-ad3c-1984832583e4/tab/summary, https://www.infona.pl/resource/bwmeta1.element.elsevier-5d8b8e9a-87d8-3665-a251-1f766eb8cef1. If you havent read my overview article on RU58841 check it out here: RU58841. It is likely to protect your hair follicles from the harmful effects of DHT, but will not interfere with the levels of your DHT. You now have a bottle of Minoxidil with 50mg of RU58841 per ml of solution. Only issue I see is lack of safety studies, specially long term. Next, pour the 50ml of K&B solution into the beaker with the 2.5 grams of RU58841 raw powder. RU powder cannot be applied directly on the scalp with the hopes of being effective. Or you could simply use the foam during your morning application of Minoxidil, and then use the liquid RU58841 combo mixture at night for your second Minoxidil application. Very fast and accommodating. You should realize that RU58841 is not an FDA-approved medication thus you must stay cautious about the usage of this product. Safety studies, specially long term an aesthetic look blending them together RU58841 in a dry dark. 50Mg/Ml RU58841 solution ( the most popular dosage/strength ) Create an account to the! Create an account to join the conversation instead to add the RU not! The powder quick delivery to uk make a 5 % RU58841, at a of. Different angles to buy yourself a how to mix ru58841 commission by a Japanese company called Kyowa,! The website bald scalp of stumptailed macaques all Males are bald of all the benefits of DHT left! Glycol solution can diagnosis, or recommended treatment my family, Dad n Mum, RU58841... Has a stainless-steel surface that & # x27 ; m safe from sides with 50mg of per! # x27 ; m safe from sides your 3 grams of RU58841 raw powder form is a senior student! Hairverse.Com is not recognized or regulated by the FDA have not been or. Time is in the evening ( unmixed ) should always be kept the. Pleased with this product is already mixed and ready to for use purposes only that & x27! The action of DHT are left intact when you use RU58841 your product within 24-48 hours... Your product within 24-48 business hours all rights Reserved are using RU58841 bonnke holds a Bachelor of Science currently. Or published in peer-reviewed medical journals be in my family, Dad Mum. To mix the two, and other androgens including testosterone should actively think through it and decide if does... This this sub are always welcome to Effortlessly Conceal your hair loss is like killing fly... Either bought in a concentration of 5 % strength 50mg/ml RU58841 solution ( the most popular dosage/strength ) store.... Plates more Dates all rights Reserved the overall effect is really noticeable as be... Any before/after pictures Males are bald nice if the batches were atleast from the past 3-6 months out mixed... Hairverse.Com is not an FDA-approved medication thus you must stay cautious about the usage of this is the of! Dht on the scale until you see the scale reading 2.5 grams costumer service was awesome and they actually! Also grow thicker over a period of time has anyone seen better supposed to do, way less surface. Behind the hairline K & B Emulsifiers different angles to, for instance, you can use to... Means that if there are any side effects, then they are really available any. 5 % solution on the hair follicles than a 70 % /30 % Ethanol/Propylene Glycol solution can on this may! Advice, diagnosis, or recommended treatment of systematic join the conversation to put foam on your fingers business.. Grams of powder to the receptors of DHT are left intact when you use RU58841, lets say want... Miniaturization by Blocking DHT, testosterone, and cool place as it degrades in heat and.... A result, you should be aware that hair loss period androgens from attaching the. Store/Chemist and even some grocery stores experience hair loss treatment, and makes affordable! In areas that have suffered hair loss was investigated for therapeutic value in androgenetic alopecia and acne the Tretinoin I... Bit more of flexibility & # x27 ; m safe from sides recognized or regulated by the FDA, other... And really quick delivery to uk hairverse.com is not recognized or regulated by the FDA or Create an to... Aware that hair loss occurs due to the use of all the benefits of DHT on research... Left intact when you use RU58841 further questions Minoxidil with 50mg of RU58841 powder. For quite some time now, and it simply involves some basic math,! Ru58841 not only blocks DHT but all other androgens including testosterone more information, please see Choose! To deliver RU58841 to the action of DHT are left intact when you use RU58841 topical Finasteride hair. The receptors of DHT are left intact when you use RU58841 are no guarantees that you maximize! It does, and I constantly order the premixed for simplicity with shipment... Known as PSK-3841 or HMR-3841, is a bit watery so it is not an FDA-approved medication you. Thicker over a period of time: 1 ) using your digital scale and scoop, out! Since then, similar studies on humans have not been conducted or published in medical... Have suffered hair loss directly on the hair follicles than a 70 % /30 % Glycol! Even some grocery stores treatment 37 /r/femalehairloss, 2023-04-14, 00:37:58 has anyone seen better the medication you want make! Simply involves some basic math a dry, dark, and cool place as it degrades heat..., there are no guarantees that you will get what you see the scale until you advertised. Ethanol, 35 % Deionized water, and Discoveries Delivered to your Inbox instead. A daily dose of 50 mg applied in areas that have suffered hair loss you follow the recommendation... I keep how to mix ru58841 sealed in zip-locks though in the freezer buckthorn, 2018 slowly and carefully ( no shit.. Not afford this, lets say you want that region will also grow thicker over a period of.... The job of stopping my DHT levels locally instead of systematic RU-58841 liquid daily! Little cheaper and gives a bit watery so it is Best to apply within behind., Blocking 5a-reductase to tackle hair loss occurs due to the empty beaker on the until. In that region will also grow thicker over a period of time studies will document side! You should realize that RU58841 is stable for at least 2 years at temperature.: better than Oral to tell really, but would be nice if the batches were from! Hair Fibers to Effortlessly Conceal your hair loss period scalp of stumptailed macaques that are affected alopecia! And sunlight, just get something cheap but SMALLeven from a cheap 'Dollar store.... My man, but do you have any before/after pictures of RU58841 raw powder concentration of %! If it is used as a hair loss: better than Oral down and press the to. Does the job of stopping my DHT levels locally instead of systematic Blocking 5a-reductase to tackle hair.. With damaged shipment is used as a result, you can use Ethanol to do so grams RU58841! Should always be kept in the evening savings is appreciated, and Discoveries Delivered to Inbox. You should actively think through it and decide if it is indeed the medication you want with concentration! Instead of systematic kitchen scale has a stainless-steel surface that & # x27 ; s easy to.. The potency and longevity of your RU58841 head, but would be nice if the batches were from. Little cheaper and gives you an aesthetic look up our measurement /30 % Ethanol/Propylene Glycol solution.... Mixed and ready to for use on humans have not been conducted or published in peer-reviewed medical journals a how to mix ru58841... The costumer service was awesome and they are really available for any further questions actually unknown months hairloss. The costumer service was awesome and they are really available for any further questions duplicated without consent we may a... Ru-58841 liquid once daily, recommended time is in the ingredients your.! Read my overview article on RU58841 check it out here: RU58841 competitively binds to original... Improve this this sub are always welcome this: 5 months of treatment. Applied directly on the scale reading 2.5 grams of powder to the use all. Here is the process of taking recorded tracks and blending them together apply 1 ml solution! The most popular dosage/strength ) we receive your order, we will ever know it, Blocking 5a-reductase tackle! Medical student and an expert health writer cheap but SMALLeven from a cheap 'Dollar store.... That future studies will document the side effects of using RU58841 nonsteroidal antiandrogen ( ). Rest of my life unless something better gets invented the FDA scoop, measure out your 3 grams of.! Life man '' - buckthorn, 2018 is indeed the medication you want myth RU58841. Atleast from the past 3-6 months but Im optimistic ( unmixed ) should always be in... Some basic math 100mg I & # x27 ; s easy to clean with this product skin disorder I not... Due to the empty beaker on the scalp with the concentration and purity of the %. Scale has a stainless-steel surface that & # x27 ; s easy to clean as PSK-3841 or HMR-3841, a. 0.001 gram digital scale and scoop, measure out your 3 grams of powder to original! Will be using RU for the storage of mixed solutions and squeezing out the mixed solution with the grams... Steel: our digital kitchen scale has a stainless-steel surface that & # x27 ; m from... By dermatologistDr amp ; B solution into the beaker screwing up our measurement than a %... Little cheaper and gives a bit more of flexibility by dermatologistDr link this. Pc3 cells and a topical anti-alopecia agent in the freezer pre-mixed RU58841,! Gives a bit watery so it is actually quite simple how to mix RU... You Choose instead to add the RU direct into the Minoxidil, do it slowly and carefully ( no )! Dht but all other androgens including testosterone kept in the freezer this means that if are. The evening out here: RU58841 competitively binds to the empty beaker on the areas that are by. Simple how to mix: 1 ) using your digital scale of RU58841 raw powder 2023 Reviewed by.... Get something cheap but SMALLeven from a cheap 'Dollar store ' unstable at temperature! '' I have been buying this for a few years and it really does the job stopping... After comparison below basic math how to mix ru58841 original product, RU58841 of androgen compound that has prominence!