Took to vet and she said it could be the Simparico Trio. She was ok for awhile, then she had a seizure and started throwing up all over the house. I wish I read these side effects before my vet recommended Simparica Trio for my 12 week old Bichon. Which Type of Dog Fence Is Right For Your Pet? These include vomiting, diarrhea, lethargy, inappetence, itching, and, very . The seizure has finally stopped and he seems to be sleeping peacefully. I will not give it to my puppy again, but what is a safer med. I am so worried about her I called to explain and was told to feed her chicken and rice and if she isn't improved take her to Emergency Vet Hospital. When fleas or ticks bite, they are exposed to its FDA-approved ingredient sarolaner, the insecticide, and acaricide that kills parasites fast. He never ever used to do this. After reading theses comments I started looking into SIMPARICA TRIO. This neurotoxin destroys fleas, ticks, and other insects for 35 days after your dog takes the medicine. Yes Id like to know that answer myself. Never again will I be giving my pets any pharma meds. and you expect people to give this to their beloved pets? Sometimes I think he is either blind or deaf. So no Addisions. She gave her a shot to keep her from throwing up and took her x-rays and told me to come back the next day if she wasn't better. Vet says Simparica is not the reason for his condition, but he was totally fine prior to taking Simparica!! But anyways - the other night , his feet collapsed from under him & he fainted . A heartworm test may be necessary in about six months (that's how long it takes heartworm larvae to mature enough to show up on a test). This time I am seeing a little blood or tissue in her stool. I quit the canned sweet potatoes (he loved them) thinking it was the syrup, that I drained anyway before adding to mixture. The initial trial had seizure results but supposedly only in dogs with seizure history. He does well on Simparica trio and also has the Lyme shot ? Im going to keep a close watch on him over the next few days. After doing more research on their monthly medication, I will no longer use Simparica Trio nor ever recommend it. I am also very worried about him. Even with what she has been through we have to wait until Dec 1st to see the Neurologist as there is only one in the State of Maine. He is not the same puppy prior to two days ago! I've beaten myself up so much giving her this drug, I felt I could trust the vet and the drug company but we obviously cant and it's all about making more money. The vet just gave our 16lb shorkie this on Tuesday and he still has the tremors really bad and very lethargic, Im very worried and concerned. All went well until this morning. I threw him his ball and he actually was interested in it. Instead it has become a world of greed. . First dose was on 4/1 and 9 days later he was vomiting goop (yellow thick goo), he would drink water and vomit. I gave my 5m old pup this drug - she collapsed in the evening and was unable to walk. Monday morning - 11 days after he is like a zombie - all motions are almost mechanical and when I talk to him it takes him a long while to react. The Simparica was recommended by the vet. Now Im scared ive been giving him Simparica Trio and it could be the cause of his progressively worsening sickness. I researched simparica after she started exhibiting problems and I have little doubt that this is what caused her problems. He also had a blood test done and all was normal. My 12 yr-old Chihuahua mix is losing his hair right above his nose. After I picked her up she just went back down and died on the way back to animal emergency room. Over two weeks later she still can not walk properly. Also what are you looking at giving your dog as a seizure medication?? My veterinarian did not warn me of these and now my precious boxer is gone!!!!! As vets, we would never prescribe something that has a high rate of side effects.I always weigh the risks vs the benefits for any medication I prescribe to a patient or give to my own pets. My other Lab after 5 days started having severe diaherria (black at first, now golden) and now throwing up too. Sarolanerstarts fighting fleas within three hours and begins to kill ticks after 8 hoursincluding the lone star tick, black-legged tick, brown dog tick, American dog tick, and Gulf Coast tick. Are there any side effects of using Simparica TRIO for the dog? Hope your pup is doing better!! First it was a fake guess of Lyme (she's from Texas where Lyme is not) disease diagnosis and $1200 wasted. GAGA-gated channels help to calm nerve transmissions, which sarolaner alters, creating an influx of nerve transmissions. Vet office said make sure to give with food. 5 hours after the dose she's home resting. Youre an idiot then! I just hope he has a turn around . Wednesday morning at 5am she awoke with bloody diarrhea and it turned into just blood. It seemed impossible that our boy could age years in literally 3 days. I'm so angry this medication is on the market. Most of us dog parents use some form of heartworm prevention for our dogs. In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions. My 15 yr old doodle wasnt given bravecto because of reviews. If this was our children and you went to your doctor for a shot, and the Dr. said "don't worry, only 1% of kids get seizures or other problems from this shot, we wouldn't stand for it. Simparica has not been evaluated in pregnant, breeding or lactating dogs. I took her home. She seems to have aged five years since T-Day. He had soft poop right after I give him the pill then got worse yellow diarrhea for about a week also vomiting he fine now they changed the medication. I hope for all of you that your pets (loved ones) have improved, I know the feeling of total helplessness to help them and all you can do is wait and hope. Just gave my baby her first dose. She hasnt eaten in 3 days and is unable to go up 2 simple steps. I even said "I am reading a blog, right now, with pages of stories about this drug and the side effects". DO NOT give this poison to your pets. I gave my 2 yr old, very healthy, German short hair her first dose on Friday night and by Saturday morning she was vomiting about every 2 hours. Side effects of Simparica Let us now look at possible side effects when administering Simparica. And now I'm upset with myself for giving this to my dog without doing research. Never any issues with bravecto so we'll return to that medication. We asked our vet, but he ignored the question. $20.45 Trifexis Chewable Tablets for DogsRx Product Details Product Description Simparica Trio Chewable Tablets for Dogs works to prevent heartworms as well as treat lone star ticks, black-legged ticks, Gulf Coast ticks, American dog ticks, brown dog ticks, fleas, roundworms, and adult hookworms. Today June 1,2022 she is still having neurological problems. Although most dogs and cats handle this powerful pesticide just fine, others can have severe reactions, the U.S. Food and Drug Administration said Thursday. It all depends, sadly. This may post twice - I didn't see my original post so I'm trying again! My vet recommended the tablet to save on monthly costs for flea and tick treatment. We rushed him to the emergency vet and they put him on keppra to stop the seizures. My dog was super sick the first months of his life. Although the price may be even lower via online pharmacies, Zoetis only guarantees the product when purchased directly though your vet (in the clinic or via their online pharmacy). Well, let me tell you: THANK YOU ALL FROM THE BOTTOM OF MY HEART. 8 months of prednisone and around the clock nursing care at home saved her life. He now cannot go in the car anymore. Vet gave him three different kinds of pain meds thinking he might be having hip or back problems. Has anyone else experienced this? I returned to vet next day with him and was advised he was ok. He is pissing a lot and often and drinking a lot of water. He's been in an emergency hospital for two nights, no signs of improvement despite blood transfusions and other symptoms. I would not recommend giving Simparica to your pets!!!!! He walked outside peed then tried to come back in the house but his legs gave out . My dog was under the 6 month mark that most dogs start idiopathic epilepsy, he could not have had a history. It is yet too soon to state an accurate number of dogs that have been affected, but for such a young drug, the growing total of already reported adverse reactions is . Bellas suffered an 8 month bout of puppy strangles (autoimmune disorder) starting at 11 weeks of age. Pyrantel Pamoate got its approval for the first time by the FDA for the purpose in 1977. We took him to vet and they gave nausea meds and kept him overnight. The reason I had stopped it , I saw a Instagram where a girls dog took the. Things like: tremors decreased conscious proprioception ataxia reduced or absent menace, and or seizures Simparica is not recommended in lactating, pregnant females, or dogs used for breeding. He is back to his old self now but we will never give him this medication again. She became extremely lethargic and feverish so we rushed her to Hospital. In addition to killing fleas and several kinds of ticks, Simparicais effective in preventing and treating mange and ear mites. This Tuesday the 17th I had given my dog simparica trio for 27lbs dose. I did and they said they are going to report it to the FDA. He has become more aggressive and has been growling at me sometimes when I try to move him. Hello! Im now scared half to death. I only stumbled on the side effects of this drug via a post on a Spinone group. Contrary to the statement in that same above article "The results are fatal for fleas and ticks but safe for mammals such as your dog." Our Vet suggested Simparica Trio! As per the vet, Simparica is an excellent flea and tick product that is available in oral form. If she had just taken it they could give her Charcoal. The vet and company are in consultation. Like other oral treatments, Simparicaworks by entering a dogs bloodstream immediately after ingestion. How common are Simparica side effects? So, again, tears in my heart, THANK YOU ALL SO MUCH for your generous information. She is still eating but she is drinking more water. She went on 2 antibiotics, and medicated baths twice a week. I need to tell my vet to switch! We received the first dose of this medication from our Vet! The vet doesn't seem to really want to blame it on Simperica Trio and wants to treat these symptoms which he says are life threatening. She started it on 7/22. High on the list was Simparica Trio. His motor skills have been affected and hes been losing weight even though he eats heartily. She looked it up and said they were a ton of recalls and she admitted to me that that is what possibly killed him because it was on the recalls and theyd had mini dogs come in for the same issue. Them I took him to a vet for check up and to my horror, he has fleas and a tick. To make dosing easy, it's available for dogs in six sizes based on body weight range: Simparica Trio can be given to dogs with or without food. I feel like the simperica trio has somehow affected his Pituitary/Andrenal glands are maybe even acting as blockers to them. Anyway, he prescribed him pain relief for 7 days. I dont like that my dog looks at me like he doesnt know who I am. Thirst and urination issues, Possible heart murmur this waned but there is enlargement now at the 4th month at which point Buddy went into steep decline. Is your puppy better now and how long did his symptoms last for? Today he wont eat, is sleeping all day, and when he is up he is panting heavily. My dog was HEALTHY and HAPPY prior to giving him this drug and literally days later he is struggling to recover. Now that Ive read all these comments I think he has developed these issues because of this trio medication. Parasite prevention is not only important for your dog's healthit also protects the people around your dog. These signs usually resolve without treatment. I have a completely different dog. Shortly after tablet I introduced sweet potatoes to diet per vet in lieu of potatoes. Banfield Hospital pushed" Simparica Trio" on our 16 year old Toy Poodle which caused a neurological disorder of sundowner to the point of him having two days straight of constant seizures, repetitive pacing and extreme agitation. So if your dog actually has meningitis then that wouldn't be related to having given him Simparico but a separate matter altogether. Topical only for me from now on. It's not worth the risk of additional seizures or other neurological effects, and it seems that his stumbling and getting tired sooner on walks are likely related. So here we are on the 2nd dose. Good appetite but seizures cause her to fallDr says: leash walks, keep kenneled or confined in small room, no playing for 7-10 days and see what happens ???? Was prescribed Simparica Trio for my Catahula dog with no medical issues. At the same time, Simparica Trio is used to prevent heartworm and lungworm disease (both caused by blood worms that infect the heart and blood vessels supplying the lungs). Ekko then started having seizures in May,June and July. After reading all your entries, i'm thrilled i chose to take her off of it. I have a person that bought a husky puppy from me March 6 @ 6 weeks old. This medication must really be strong to do Flea tic and heart worm etc. We nurses him back into a happy healthy puppy and now this. There is a petition in Australia to have this drug banned through change.org, which I've signed. Strictly natural with zero side effects from now on. Does your do still have a cough? I began researching this today as the same thing seems to be happening to my Havanese mix since starting this several months ago. PROS Treats adult fleas and prevents flea and tick infestations Effective against five types of tick Liver flavored tablet FDA Approved CONS Hes not well..we hope he recovers fully! Hi Chelsea, I am hopeful that your Shepherd has recovered. I left a lot out but didnt want to make too lengthy post. I am so incredibly upset with myself for trusting my vet and giving my dog this product. All other pets in the home must also be treated with a flea control product for a minimum of 30 days prior to the report. I gave 2 of my older Labs a dose of Simparica on a Saturday. my vet recommended this for both my yorkies. Nothing stopped the seizures and our Pickles passed away after just a few months of symptoms. I realized it was from the simparica. Hoping we dont have any more issues and will not be giving this again. Thursday morning was an awful beginning of the day for our boy. I am so mad at the vet and think we should file suit against this company. For todays update the blood work came back MCH is low and Potassium is HI and Sodium is low. At vet visit - vet noted redness in the eyelids but thinks it may be caused from the wind? I'll be spreading the word. They both got similar issues and this was the only thing they both did. Instead, it kills larvae, allowing your dog to avoid infection. Not Trio because of all the seizure horror stories. Sorry, cant see you for 4 days. My 3 month old shih tux Juno took her second dose last week and for the last two days shes vomited and has been eating grass nonstop! Simparico Trio, will not be given to my dog ever again. I have paid about $500 - $600 to heal the little King, but it's not working. No problem eating. I'm also wondering if his anxiety is related as well. My dog steadily went downhill after I gave her the first dose of simparica. I brought him to the vet and they keep trying to say excessive water drinking isnt a side effect but its the only thing that is different that Ive given my pup. No more of this med! I dont want to have to put my dog down but hes suffering. Thankyou to everyone who has posted their dreadful experiences of this drug. No diarrhea or vomiting or seizures. I too would like to know how long this symptom lasted in other dogs who experienced the same issue. We have spent well over $5000.00 and upset about all the horror stories we are now hearing. Will NEVER give this to my dog again. I disagree. She still coughs, sneezes and brings up lots of mucus. Im throwing away the remaining 5 pills and going back to a topical medicine. Can blocking GABA receptors also cause inflammation of spine? A week and a half from taking the drug, he is still on 3 meds, taking fluids and starting to gain strength and eat food and drink water in very small amounts. I lost my girl 2 days after taking Simparica. We may also give additional medications to keep fleas, ticks, and common intestinal parasites away. This is whats happening to our pup, can you please tell me how long it lasted? We go for more bloodwork today and are praying for better news. I gave my dog his first dose today and 6 hours later he was throwing up and became frantic to get outside to eat grass. She had the treatment yesterday and seemed ok. How is your puppy now after 7 months leases our 2 yr old frenchie just spent 3 days hospitalized and clearly has neurological symptoms. Pyrantel pamoate is a nematocide (kills some worms) belonging to the tetrahydropyrimidine class. For the treatment and control of tick infestations with Amblyomma americanum (lone star tick) and Ixodes scapularis . I knew it was bad from the onset but the vet said I can't take a chance on him getting heartworms because the mosquitos are so bad not to mention fleas and ticks. I know Dukes problems were from this medicine, and it upsets me that my vet told me that this medicine was safe! Im beside myself. She has been on it for 6 months. Im still confused. Our dog was killed by this poison within 15 hours after taking one dose. Simparica chewable is a preventative that is better suited to healthy adult dogs living in areas where ticks are prevalent. I had a trainer come in the day of, and he was with me the all day, NOTHING a happened for him to be in pain! I wouldnt have given it to her. Needless to say, we will no longer be giving this to our lab or our other dog. My nearly 14 year old Havanese Kokomo has taken a sharp decline in the last 8 month and I was blaming it on old age when I think I may have been poisoning him. My dog is having seizures. We have an appt for a skin scraping. He could not hold down any food or water. At first B seemed fine. In January, he was boarded and the boarder asked us if he could possibly be blind. Side effects with Simparica are not common. Sarah thanks for your response! Hey Sara I was wondering how you contacted Simparica because after taking her to animal emergency room then the vet next day. I just gave my Matty her first dose. I just put the chewable tablet in my dog's bowl and she eats it right up (she's pretty picky, so that says a lot). Don't trust your vet, do your own research. They don't really have an answer for why this happens at all, or why some dogs get better and some don't. Started downhill health issues with initial dose. We gave our 3.5 month old Aussie pup a dose of Simparica today (vet's prescription), and I did not see the warnings about giving it to dogs under 6 months. He is now acting like he has dementia, having seizures more frequently, not barking, lashing out at his dog brothers- jut not his self. Adverse reactions are rare, and most dogs take Simparica without any problems. I will NEVER give this drug to my dogs! Puppy is having seizures and has aspirated pneumonia. Simparica TRIO also works for the control and treatment of adult hookworm and adult roundworms. Next she developed severe tremors. I just gave Bentlee my Akita Simparica Trio on the 9th. Is Simparica only available with a prescription? Hi, Im wondering whats going on with your dog now? Unlike Bravecto, Simparica hasn't been tested on pregnant, lactating, or breeding dogs. I am so upset - I gave it to him last week and he had an accident in the house. Vets at Petsmart should know better; changing vets. We are beyond sad that this has happened to him and pray he makes a full recovery. Still waiting to find out of she has progressed. Now I have to pay $100's of dollars on meds to check her antibody and possibly put her on meds for life . My vet recommended this for my puppy, he is now lethargic, has blood in stool, and can hardly stay awake. We are experiencing the same thing. My vet is aware of this and prescribed simparica. He was on comfortis oral for years with no issues. And for those who have lost their fur babies I am so sorry for your lost. Im so angry at these drug companies and vets for selling this crap. Why would he knowingly recommend this? 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